Download Bacterial and Bacteriophage Genetics by Edward A. Birge PDF

By Edward A. Birge

ISBN-10: 0387239197

ISBN-13: 9780387239194

Genetic investigations and manipulations of micro organism and bacteriophage have made important contributions to our simple figuring out of residing cells and to the improvement of molecular biology and biotechnology. This quantity is a survey of the genetics of micro organism and their viruses, and it presents scholars with a finished creation to this speedily altering topic. The ebook is written for top point undergraduates and starting graduate scholars, relatively those that have had an introductory genetics course.

The 5th version has been largely revised to mirror contemporary advances within the box. The e-book now has a reader-friendly glance, with end-of-chapter questions, "Thinking forward" and "Applications" bins to problem scholars’ comprehension and insights. an entire thesaurus of widely used phrases has been revised and increased.

Show description

Read or Download Bacterial and Bacteriophage Genetics PDF

Best viral books

Dictionary of Parasitology

Even supposing many books were released on a variety of features of human, animal, and plant parasitology, in addition to the general public illnesses linked to parasites, none so far has provided a complete word list for these faced with the discipline's enormously vast terminology. to fulfill this want calls for a devoted textual content which may condo the myriad entries that outline the entire uncomplicated rules and complicated nomenclature of parasitology.

Transgenic Models of Human Viral and Immunological Disease

Such a lot ailments are multifactoral. Transgenic know-how allows gene(s) of curiosity to be expressed in a small manipulatable laboratory animal version. by way of this technique, murine versions of human infections should be constructed and studied; results of cytokines in vivo, focally expressed in detailed cells will be verified and manipulated, and numerous autoimmune problems, mimicking human affliction should be built.

African Horse Sickness

African horse affliction virus is a double-stranded RNA virus which reasons a non-contagious, infectious arthropod-borne sickness of equines and infrequently canines. 9 detailed, the world over known serotypes of the virus have thus far been pointed out. This e-book is predicated upon the findings of 2 programmes funded through the ecu fee.

Additional info for Bacterial and Bacteriophage Genetics

Example text

DNA polymerase III is responsible for the bulk production of DNA. Its action is rapid, and it can join together up to 60,000 nucleotides per minute. It also has a proofreading capability, a 3′→5′ exonuclease activity that allows the enzyme to “backspace” if an incorrect base has been inserted. 1). 1. Major E. coli genetic loci involved in DNA replication. Genetic Locus in Bacteria (E. 1. (Continued) Genetic Locus in Bacteria (E. coli) Protein Function Lig (NADdependent) NrdAB PolA, RNase H PolC RpoA RpoB RpoD Ssb DNA ligase; joins Okazaki fragments Ribonucleotide reductase that synthesizes deoxyribonucleotides from ribonucleotides Removal of primers, repair enzyme Removal of primers, repair enzyme α Subunit of DNA polymerase III; polymerase function α Subunit of RNA polymerase β Subunit of RNA polymerase σ Subunit of RNA polymerase; responsible for normal promoter binding Single-strand DNA binding protein; facilitates melting of helices and stabilizes single strands Functional Equivalent in Archaea DNA ligase I (ATP-dependent) Flap endonuclease I RNase H RPA/SSB The number of proteins involved in DNA replication is far greater than what can be summarized in one table.

Genetics 54: 61–76. , Deighan, P. (2003). Regulation of gene expression by histone-like proteins in bacteria. Current Opinion in Genetics & Development 13: 179–184. , Scheffers, D. (2003). Cytokinesis in bacteria. Microbiology and Molecular Biology Reviews 67: 52–65. N. )(2004). The Bacterial Chromosome. Washington, DC: ASM Press. , AllardetServent, A. (1998). Unconventional genomic organization in the alpha subgroup of the proteobacteria. Journal of Bacteriology 180: 2749–2755. Lederberg, J. (1987).

The predominant impression of isolated nucleoids is one of coiled DNA. This complex structure consists of 60% DNA, 30% RNA, and 10% protein. It consists of superhelical coils that result from twisting an entire DNA helix over and above the normal helical turns. This is roughly equivalent to taking a twostranded wire rope, coiling it on the ground, and then gluing the ends together so that the extra turns become an integral part of the structure and give a torsional tension to the structure. On a molecular scale, superhelical turns are added or removed by a group of enzymes known as topoisomerases, which act to change only the topology of a DNA molecule and not its base sequence.

Download PDF sample

Bacterial and Bacteriophage Genetics by Edward A. Birge


by Anthony
4.0

Rated 4.45 of 5 – based on 27 votes