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By Adriel R. Bonilla

ISBN-10: 1607416239

ISBN-13: 9781607416234

ISBN-10: 1607419734

ISBN-13: 9781607419730

ISBN-10: 1616681624

ISBN-13: 9781616681623

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Plantarum and L. paracasei was more than 256 µg/ml, while it was less than 2 µg/ml for L. acidophilus (Danielsen and Wind, 2003). , 2005). , 2008). , 1999). E. faecium isolated from food or patients have highly variable resistance profiles, even though many are acquired traits (Mathur and Singh, 2005). , 2005). The extensive and imprudent prescription of antibiotics has resulted in a selective pressure for point mutations and the acquisition of genetic elements encoding resistance. , 2008). Under natural conditions, the dissemination of resistance genes occurs at three superimposable levels: bacterial epidemics (resistant bacteria transferred among mammals), Antibiotic Resistance and Probiotics 21 plasmid epidemics (resistance gene located in a conjugative plasmid) and genetic epidemics (resistance genes that are part of a transposable element).

2007) conducted the first study investigating the effects of antibiotic therapy on the antibiotic susceptibility of simultaneously ingested probiotic strains. The authors investigated the effects of oral therapy with tetracycline-based antibiotics on the probiotic strains L. acidophilus LaCH-5 and B. animalis subsp. lactis Bb-12. A higher proportion of tetracycline-resistant anaerobic bacteria and bifidobacteria was detected in the subjects taking antibiotics than the control group subjects. In addition, several subjects taking antibiotics had fecal B.

Lactobacilli possess prominent intrinsic resistance to bacitracin, cefoxitin, ciprofloxacin, fusidic acid, kanamycin, gentamicin, metronidazole, nitrofurantoin, norfloxacin, streptomycin, sulphadiazine, teicoplanin, trimethoprim/sulphamethoxazole and vancomycin (Danielsen and Wind, 2003). , 2005). Strains of Lactobacillus delbrueckii subsp. bulgaricus that are widely used as a yogurt culture have been repeatedly found to possess intrinsic resistance against mycostatin, nalidixic acid, neomycin, polymyxin B, trimethoprim, colimycin, sufamethoxazol and sulphonamides (Mathur and Singh, 2005).

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Antibiotic resistance : causes and risk factors, mechanisms and alternatives by Adriel R. Bonilla


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